Name	RNF19B
Full Name	E3 ubiquitin-protein ligase RNF19B
Synonyms	IBR domain-containing protein 3, Natural killer lytic-associated molecule, RING finger protein 19B \| IBRDC3, NKLAM
Primary ID	Q6ZMZ0
Links	- -
Type	protein
Relations	4
Function	E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1 (PubMed:16709802, PubMed:27485036). Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells (PubMed:10438909). Protects against staurosporin-induced cell death (PubMed:27485036).