Summary

Name SRCAP
Full Name Helicase SRCAP
Synonyms Domino homolog 2, Snf2-related CBP activator | KIAA0309
Primary ID Q6ZRS2
Links - -
Type protein
Relations 2
Function Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation KLK3 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding AR 0.42
Publications: 1 Organism: Homo Sapiens