Summary

Name RUFY3
Full Name Protein RUFY3
Synonyms RUN and FYVE domain-containing protein 3, Rap2-interacting protein x, RIPx, Single axon-regulated protein, Singar | KIAA0871
Primary ID Q7L099
Links - -
Type protein
Relations 1
Function Plays a role in the generation of neuronal polarity formation and axon growth (By similarity). Implicated in the formation of a single axon by developing neurons (By similarity). May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes (By similarity). Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery (PubMed:25766321). Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones (By similarity). Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner (PubMed:25766321).

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png phosphorylation RUFY3 0.277
Publications: 1 Organism: Homo Sapiens