4.0
Summary
| Name |  DHX30
|
| Full Name | ATP-dependent RNA helicase DHX30 |
| Synonyms | DEAH box protein 30 | DDX30, KIAA0890 |
| Primary ID | Q7L2E3 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Pathways | Innate Immune Response |
| Function | RNA-dependent helicase (PubMed:29100085). Plays an important role in the assembly of the mitochondrial large ribosomal subunit (PubMed:25683715, PubMed:29100085). Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity). Associates with mitochondrial DNA (PubMed:18063578). Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | DHX30 | up-regulates 
|
Stress_granules | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | Innate Immune Response | |||
| + | DHX30 | down-regulates quantity by repression 
transcriptional regulation
|
FASTKD2 | 0.383 |
| Publications: | 1 | Organism: | Homo Sapiens | |