Summary

Name FASTKD2
Full Name FAST kinase domain-containing protein 2, mitochondrial
Synonyms FAKD2_HUMAN | KIAA0971
Primary ID Q9NYY8
Links - -
Type protein
Relations 2
Function Plays an important role in assembly of the mitochondrial large ribosomal subunit (PubMed:25683715). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664, PubMed:25683715, PubMed:26370583). May play a role in mitochondrial apoptosis.

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Relations

Regulator Mechanism target score
+ up-regulates img/indirect-activation.png Stress_granules 0.7
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation FASTKD2 0.393
Publications: 1 Organism: Homo Sapiens