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Summary
Name
NRK
Full Name
Nik-related protein kinase
Synonyms
EC 2.7.11.1 |
Primary ID
Q7Z2Y5
Links
-
-
Type
protein
Relations
1
Function
May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway (By similarity). {ECO:0000250}.
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by mechanism
none
polyubiquitination
by effect
none
down-regulates quantity by destabilization
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
HEK-293 cell
Relations
Regulator
Mechanism
target
score
ℹ
+
STUB1
down-regulates quantity by destabilization
polyubiquitination
NRK
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-274110
Homo sapiens
HEK-293 Cell
pmid
sentence
32162334
Our results indicate that Nrk is ubiquitinated by CHIP in a chaperone-dependent manner, resulting in its proteasomal degradation.
Publications:
1
Organism:
Homo Sapiens