Summary

Name POGZ
Full Name Pogo transposable element with ZNF domain
Synonyms Suppressor of hairy wing homolog 5, Zinc finger protein 280E, Zinc finger protein 635 | KIAA0461, SUHW5, ZNF280E, ZNF635
Primary ID Q7Z3K3
Links - -
Type protein
Relations 2
Function Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding AURKB 0.329
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding CBX5 0.443
Publications: 1 Organism: Homo Sapiens