Summary

Name IRF2BP2
Full Name Interferon regulatory factor 2-binding protein 2
Synonyms IRF-2-binding protein 2, IRF-2BP2
Primary ID Q7Z5L9
Links - -
Type protein
Relations 2
Function Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities (PubMed:12799427). Represses the NFAT1-dependent transactivation of NFAT-responsive promoters (PubMed:21576369). Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles (PubMed:20702774). Plays a role in immature B-cell differentiation (PubMed:27016798).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination IRF2BP2 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding IRF2 0.652
Publications: 1 Organism: Homo Sapiens