| + |
PBRM1 | up-regulates quantity by expression 
transcriptional regulation
|
CDKN1A |
0.265 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-178022 |
|
|
Homo sapiens |
Breast Cancer Cell |
| pmid |
sentence |
| 18339845 |
Endogenous wild-type baf180 bound to the p21 promoter and was required for proper p21 expression and g(1) arrest after transforming growth factor-beta and gamma-radiation treatment. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PBRM1 | up-regulates quantity by expression
transcriptional regulation
|
RARB |
0.429 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-132378 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15601824 |
We found that baf180 deficiency leads to a decreased expression of select target genes, such as s100a13 and ra targets rar_2 and crabpii in heart tissues. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PBRM1 | up-regulates quantity by expression
transcriptional regulation
|
S100A13 |
0.455 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-132431 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15601824 |
We found that baf180 deficiency leads to a decreased expression of select target genes, such as s100a13 and ra targets rar_2 and crabpii in heart tissues. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Heart |
| + |
PBRM1 | form complex 
binding
|
SWI/SNF ACTL6B varian |
0.774 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270596 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30397315 |
Mammalian SWI/SNF (mSWI/SNF) complexes are ATP-dependent chromatin remodelers that modulate genomic architecture and DNA accessibility, enabling timely and appropriate control of gene expression. They are combinatorially assembled from the products of 29 total genes into three final-form complexes: canonical BAF, PBAF (polybromo-associated BAF complexes), and a newly-defined non-canonical BAF (ncBAF), with specific subunits specifying distinct complexes, such as PBRM1, ARID2, and BRD7 in PBAF complexes, ARID1A/ARID1B and DPF2 in canonical BAF (cBAF) complexes, and GLTSCR1/GLTSCR1L and BRD9 in ncBAF complexes |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PBRM1 | up-regulates quantity by expression
transcriptional regulation
|
CRABP2 |
0.431 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-131552 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15601824 |
We found that baf180 deficiency leads to a decreased expression of select target genes, such as s100a13 and ra targets rar_2 and crabpii in heart tissues. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
PBRM1
- 
- 