3.0
Summary
| Name |  ADIPOR2
|
| Full Name | Adiponectin receptor protein 2 |
| Synonyms | Progestin and adipoQ receptor family member II | PAQR2 |
| Primary ID | Q86V24 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity). |
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