Summary

Name MON1A
Full Name Vacuolar fusion protein MON1 homolog A
Synonyms MON1A_HUMAN | SAND1
Primary ID Q86VX9
Links - -
Type protein
Relations 2
Function Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).

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Relations

Regulator Mechanism target score ℹ
+ MON1Aform complex img/form-complex.png binding MON1-CCZ1 guanyl-nucleotide exchange factor complex, MON1A variant 0.852
Publications: 1
+ MON1Aform complex img/form-complex.png binding MON1-CCZ1B guanyl-nucleotide exchange factor complex, MON1A variant 0.671
Publications: 1