Summary

Name SKAP1
Full Name Src kinase-associated phosphoprotein 1
Synonyms Src family-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa, SKAP-55, pp55 | SCAP1, SKAP55
Primary ID Q86WV1
Links - -
Type protein
Relations 1
Function Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png dephosphorylation SKAP1 0.368
Publications: 1 Organism: Homo Sapiens