| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278755 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 34654719 |
Our data suggest that HUWE1 can ubiquitinate PTOV1 in vitro and depletion of HUWE1 in cells increases the stability of PTOV1 S36A protein in the nucleus.|Our data suggest that depletion of HUWE1 elevates PTOV1 protein levels, which, in turn, promote the expression of cJun, a pro-growth translational target of PTOV1 (18)\n In our model, we propose that HUWE1 mediates the degradation of PTOV1 in the nucleus. |
|
3.0
PTOV1
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- 
ubiquitination