Summary

Name IRF2BP1
Full Name Interferon regulatory factor 2-binding protein 1
Synonyms IRF-2-binding protein 1, IRF-2BP1, Probable E3 ubiquitin-protein ligase IRF2BP1, 6.3.2.-
Primary ID Q8IU81
Links - -
Type protein
Relations 2
Function Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination IRF2BP1 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding IRF2 0.715
Publications: 1 Organism: Homo Sapiens