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Summary
Name
CREBRF
Full Name
CREB3 regulatory factor
Synonyms
Luman recruitment factor, LRF | C5orf41
Primary ID
Q8IUR6
Links
-
-
Type
protein
Relations
1
Function
Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.
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by mechanism
none
transcriptional regulation
by effect
none
up-regulates quantity by expression
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
HEK-293 cell
Relations
Regulator
Mechanism
target
score
ℹ
+
CREBRF
up-regulates quantity by expression
transcriptional regulation
HERPUD1
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-261575
Homo sapiens
HEK-293 Cell
pmid
sentence
16940180
Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element.
Publications:
1
Organism:
Homo Sapiens