Summary

Name CEP97
Full Name Centrosomal protein of 97 kDa
Synonyms Cep97, Leucine-rich repeat and IQ domain-containing protein 2 | LRRIQ2
Primary ID Q8IW35
Links - -
Type protein
Relations 2
Function Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545, PubMed:30375385). Required for recruitment of CCP110 to the centrosome (PubMed:17719545). {ECO:0000269|PubMed:17719545, ECO:0000269|PubMed:30375385}.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination CEP97 0.272
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png binding CEP97 0.2
Publications: 1 Organism: Homo Sapiens