3.0
Summary
| Name |  WDFY1
|
| Full Name | WD repeat and FYVE domain-containing protein 1 |
| Synonyms | FYVE domain-containing protein localized to endosomes 1, FENS-1, Phosphoinositide-binding protein 1, WD40- and FYVE domain-containing protein 1, Zinc finger FYVE domain-containing protein 17 | FENS1, KIAA1435, WDF1, ZFYVE17 |
| Primary ID | Q8IWB7 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines (PubMed:25736436). {ECO:0000269|PubMed:25736436}. |
transcriptional regulation