Summary

Name KLHL7
Full Name Kelch-like protein 7
Synonyms KLHL7_HUMAN |
Primary ID Q8IXQ5
Links - -
Type protein
Relations 2
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png binding TUT1 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding Cullin 3-RBX1-Skp1 0.408
Publications: 1 Organism: Homo Sapiens