Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272475 |
|
|
Homo sapiens |
|
pmid |
sentence |
14633994 |
Raver1 was identified in two-hybrid screens by its interactions with the cytoskeletal proteins actinin and vinculin, and was also found to interact with PTB || Here we show that raver1 is able to promote the smooth muscle-specific alternative splicing of TM by enhancing PTB-mediated repression of exon 3. This suggests a novel mechanism for PTB-mediated splicing repression involving recruitment of raver1 as a potent splicing co-repressor. |
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