3.0
Summary
| Name |  IFNL3
|
| Full Name | Interferon lambda-3 |
| Synonyms | IFN-lambda-3, Cytokine Zcyto22, Interleukin-28B, IL-28B, Interleukin-28C, IL-28C | IL28B, IL28C, ZCYTO22 |
| Primary ID | Q8IZI9 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets |
binding