Relation Results

Name	IFNL2
Full Name	Interferon lambda-2
Synonyms	IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A \| IL28A, ZCYTO20
Primary ID	Q8IZJ0
Links	- -
Type	protein
Relations	2
Function	Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets