Summary

Name CACNA2D3
Full Name Voltage-dependent calcium channel subunit alpha-2/delta-3
Synonyms Voltage-gated calcium channel subunit alpha-2/delta-3 |
Primary ID Q8IZS8
Links - -
Type protein
Relations 5
Function The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G) (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ CACNA2D3up-regulates quantity img/direct-activation.png relocalization calcium(2+) 0.8
Publications: 1 Organism: Homo Sapiens
+ progesteroneup-regulates quantity img/indirect-activation.png CACNA2D3 0.8
Publications: 1 Organism: Homo Sapiens
+ CACNA2D3up-regulates img/indirect-activation.png Apoptosis 0.7
Publications: 1 Organism: Homo Sapiens
+ CACNA2D3down-regulates img/indirect_inhibition.png Proliferation 0.7
Publications: 1 Organism: Homo Sapiens
+ CACNA2D3up-regulates activity img/indirect-activation.png p38 0.2
Publications: 1 Organism: Homo Sapiens