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Summary
Name
MMP21
Full Name
Matrix metalloproteinase-21
Synonyms
MMP-21 |
Primary ID
Q8N119
Links
-
-
Type
protein
Relations
2
Function
Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway (PubMed:26429889, PubMed:26437028). Cleaves alpha-1-antitrypsin (PubMed:12617721).
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Relations
Regulator
Mechanism
target
score
ℹ
+
MMP21
down-regulates
ECM
0.7
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-272389
pmid
sentence
17318226
Historically, MMPs were thought to function mainly as enzymes that degrade structural components of the ECM.
Publications:
1
+
MMP21
up-regulates
ECM_disassembly
0.7
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-272366
pmid
sentence
17318226
Historically, MMPs were thought to function mainly as enzymes that degrade structural components of the ECM.
Publications:
1