+ |
PLK1 | up-regulates activity
phosphorylation
|
CNTROB |
0.323 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-279551 |
|
|
Homo sapiens |
|
pmid |
sentence |
23291182 |
However, unlike NEK2, PLK1 phosphorylation enhances the microtubule stabilizing activity of centrobin [22].|PLK1 phosphorylation of centrobin is critical for bipolar spindle formation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NEK2 | down-regulates activity
phosphorylation
|
CNTROB |
0.349 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-279545 |
|
|
Homo sapiens |
|
pmid |
sentence |
23291182 |
The opposite outcomes in NEK2- and centrobin-depleted cells suggest that NEK2 antagonizes biological functions of centrobin.|These results suggest that NEK2 phosphorylates specific sites of centrobin, which are distinct from the PLK1 phosphorylation sites. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |