Summary

Name EID3
Full Name EP300-interacting inhibitor of differentiation 3
Synonyms EID-3, E1A-like inhibitor of differentiation 3, EID-1-like inhibitor of differentiation 3, Non-structural maintenance of chromosomes element 4 homolog B, NS4EB, Non-SMC element 4 homolog B |
Primary ID Q8N140
Links - -
Type protein
Relations 2
Function Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.

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Relations

Regulator Mechanism target score
+ down-regulates img/indirect_inhibition.png Skeletal_muscle_differentiation 0.7
Publications: 1 Organism: Mus Musculus
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation EID3 0.2
Publications: 1 Organism: Mus Musculus