Summary

Name AHI1
Full Name Jouberin
Synonyms Abelson helper integration site 1 protein homolog, AHI-1 |
Primary ID Q8N157
Links - -
Type protein
Relations 2
Function Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development (PubMed:21623382).

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Relations

Regulator Mechanism target score
+ up-regulates img/indirect-activation.png Cilium_assembly 0.7
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding AHI1 0.57
Publications: 1 Organism: Homo Sapiens