Summary

Name DOCK4
Full Name Dedicator of cytokinesis protein 4
Synonyms DOCK4_HUMAN | KIAA0716
Primary ID Q8N1I0
Links - -
Type protein
Relations 1
Function Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (PubMed:12628187, PubMed:16464467). Involved in regulation of adherens junction between cells (PubMed:12628187). Plays a role in cell migration (PubMed:20679435).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png guanine nucleotide exchange factor RAC1 0.565
Publications: 1 Organism: Mus Musculus