| + |
UNC80 | up-regulates activity 
binding
|
NALCN |
0.809 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265184 |
|
|
Homo sapiens |
Brain |
| pmid |
sentence |
| 22196327 |
The NALCN complex in the brain consists of NALCN, UNC80 and UNC79. UNC80 directly associates with NALCN and UNC79 forms part of the complex by its interaction with UNC80. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265180 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 19535918 |
UNC80 is a protein that is associated with the NALCN Na(+) leak cation channel, and is required for the activation of this channel by the neuropeptide substance P through GPCRs in a G-protein-independent fashion. Here, we show that UNC80 binds Src kinases and recruits Src into the channel complex. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
UNC80 | up-regulates activity
binding
|
UNC79 |
0.803 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265183 |
|
|
Homo sapiens |
Brain |
| pmid |
sentence |
| 22196327 |
The NALCN complex in the brain consists of NALCN, UNC80 and UNC79. UNC80 directly associates with NALCN and UNC79 forms part of the complex by its interaction with UNC80. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UNC80 | up-regulates activity
binding
|
SRC |
0.351 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265179 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 19535918 |
UNC80 is a protein that is associated with the NALCN Na(+) leak cation channel, and is required for the activation of this channel by the neuropeptide substance P through GPCRs in a G-protein-independent fashion. Here, we show that UNC80 binds Src kinases and recruits Src into the channel complex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
UNC80
- 
- 