Summary

Name MTURN
Full Name Maturin
Synonyms Maturin neural progenitor differentiation regulator protein homolog, Protein Ells1 | C7orf41
Primary ID Q8N3F0
Links - -
Type protein
Relations 4
Function Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression (PubMed:24681962). Represses NF-kappa-B transcriptional activity by inhibiting phosphorylation of RELA at 'Ser-536' (PubMed:24681962). May be involved in early neuronal development (By similarity). {ECO:0000250|UniProtKB:Q7ZX36, ECO:0000269|PubMed:24681962}.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation MTURN 0.2
Publications: 1 Organism: Mus Musculus
+ down-regulates activity img/direct_inhibition.png phosphorylation MTURN 0.2
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png binding IKK-complex 0.2
Publications: 1 Organism: Mus Musculus
+ down-regulates activity img/direct_inhibition.png binding TBK1 0.2
Publications: 1 Organism: Mus Musculus