4.0
Summary
| Name |  KCTD17
|
| Full Name | BTB/POZ domain-containing protein KCTD17 |
| Synonyms | | |
| Primary ID | Q8N5Z5 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243). {ECO:0000269|PubMed:25270598, ECO:0000269|PubMed:25983243}. |
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