Summary

Name EID2
Full Name EP300-interacting inhibitor of differentiation 2
Synonyms EID-2, CREBBP/EP300 inhibitor 2, EID-1-like inhibitor of differentiation 2 | CRI2
Primary ID Q8N6I1
Links - -
Type protein
Relations 2
Function Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding SMAD3/SMAD4 0.408
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding SMAD3 0.406
Publications: 1 Organism: Homo Sapiens