Relation Results

Name	KMT2C
Full Name	Histone-lysine N-methyltransferase 2C
Synonyms	Lysine N-methyltransferase 2C, Homologous to ALR protein, Myeloid/lymphoid or mixed-lineage leukemia protein 3 \| HALR, KIAA1506, MLL3
Primary ID	Q8NEZ4
Links	- -
Type	protein
Relations	3
Function	Histone methyltransferase that methylates 'Lys-4' of histone H3 (PubMed:22266653). H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.