Relation Results

Summary

Name GPRC5A
Full Name Retinoic acid-induced protein 3
Synonyms G-protein coupled receptor family C group 5 member A, Phorbol ester induced gene 1, PEIG-1, Retinoic acid-induced gene 1 protein, RAIG-1 | GPCR5A, RAI3, RAIG1
Primary ID Q8NFJ5
Links - -
Type protein
Relations 5
Function Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR pr ...
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Type: Score: Layout: SPV 
0.3930.4EGFRGPRC5Ahsa-miR-103a-3p

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▶Modifications Tables

Relations
Regulator
Mechanism
target
score ℹ
+ EGFRdown-regulates activity img/direct_inhibition.png phosphorylation GPRC5A 0.393
Identifier Residue Sequence Organism Cell Line
SIGNOR-278333 Tyr317 EETGDTLyAPYSTHF Homo sapiens
pmid sentence
EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer.|Together, these results indicate that endogenous EGFR can phosphorylate GPRC5A at four identified tyrosine residues (Y317, Y320, Y347 and Y350) in response to EGF stimulation in the lung cancer H1792 cells.
Identifier Residue Sequence Organism Cell Line
SIGNOR-278334 Tyr320 GDTLYAPySTHFQLQ Homo sapiens
pmid sentence
EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer.|Together, these results indicate that endogenous EGFR can phosphorylate GPRC5A at four identified tyrosine residues (Y317, Y320, Y347 and Y350) in response to EGF stimulation in the lung cancer H1792 cells.
Identifier Residue Sequence Organism Cell Line
SIGNOR-278335 Tyr347 AHAWPSPyKDYEVKK Homo sapiens
pmid sentence
EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer.|Together, these results indicate that endogenous EGFR can phosphorylate GPRC5A at four identified tyrosine residues (Y317, Y320, Y347 and Y350) in response to EGF stimulation in the lung cancer H1792 cells.
Identifier Residue Sequence Organism Cell Line
SIGNOR-278336 Tyr350 WPSPYKDyEVKKEGS Homo sapiens
pmid sentence
EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer.|Together, these results indicate that endogenous EGFR can phosphorylate GPRC5A at four identified tyrosine residues (Y317, Y320, Y347 and Y350) in response to EGF stimulation in the lung cancer H1792 cells.
Publications: 4 Organism: Homo Sapiens
+ hsa-miR-103a-3pdown-regulates quantity by repression img/direct_inhibition.png post transcriptional regulation GPRC5A 0.4
Identifier Residue Sequence Organism Cell Line
SIGNOR-278004 Homo sapiens MiaPaCa-2 Cell
pmid sentence
MiR-103a-3p down-regulates GPRC5A protein by binding to the 5′ UTR of GPRC5A’s mRNA
Publications: 1 Organism: Homo Sapiens
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