| + |
LMO3 | down-regulates quantity by repression 
transcriptional regulation
|
HES1 |
0.347 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254826 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21573214 |
Luciferase reporter assay demonstrated that the co-expression of LMO3 and HEN2 attenuates HES1 (a negative regulator for Mash1)-dependent reduction of luciferase activity driven by the Mash1 promoter. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
LMO3 | up-regulates activity 
binding
|
NHLH2 |
0.422 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254827 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21573214 |
Here we found that LMO3 forms a complex with HEN2 and acts as an upstream mediator for transcription of Mash1 in neuroblastoma. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
LMO3 | up-regulates quantity by expression 
transcriptional regulation
|
ASCL1 |
0.371 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254825 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21573214 |
Overexpression of both LMO3 and HEN2 induced expression of Mash1, suggesting that they might function as a transcriptional activator for Mash1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
LMO3
- 
- 