+ |
PLPPR1 | up-regulates activity
binding
|
RASGEF1B |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261806 |
|
|
Homo sapiens |
|
pmid |
sentence |
27058420 |
Oncogenic effects of imbalanced PRG3 are mediated via PRG3-RasGEF1 interaction and Ras activation. PRG3 interacts with RasGEF1 in vivo.We could further show that PRG3 executes the binding to RasGEF1 predominantly via its C-terminal domain (CT) and in the consequence causes Ras activation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
PLPPR1 | up-regulates activity
binding
|
RASGEF1A |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261807 |
|
|
Homo sapiens |
U-87MG Cell |
pmid |
sentence |
27058420 |
Oncogenic effects of imbalanced PRG3 are mediated via PRG3-RasGEF1 interaction and Ras activation. PRG3 interacts with RasGEF1 in vivo.We could further show that PRG3 executes the binding to RasGEF1 predominantly via its C-terminal domain (CT) and in the consequence causes Ras activation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |