4.0
Summary
| Name |  ZNRF4
|
| Full Name | E3 ubiquitin-protein ligase ZNRF4 |
| Synonyms | Nixin, RING finger protein 204, RING-type E3 ubiquitin transferase ZNRF4, Zinc/RING finger protein 4 | RNF204 |
| Primary ID | Q8WWF5 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Pathways | CROHN_DENDR, ULCERATIVE_COLITIS_IBD |
| Function | E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2 (PubMed:28656966). Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum (PubMed:21205830). Could have a role in spermatogenesis (By similarity). |
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ubiquitination
ubiquitination