Summary

Name ZNRF4
Full Name E3 ubiquitin-protein ligase ZNRF4
Synonyms Nixin, RING finger protein 204, RING-type E3 ubiquitin transferase ZNRF4, Zinc/RING finger protein 4 | RNF204
Primary ID Q8WWF5
Links - -
Type protein
Relations 1
Function E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2 (PubMed:28656966). Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum (PubMed:21205830). Could have a role in spermatogenesis (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination ZNRF4 0.2
Publications: 1 Organism: Homo Sapiens