Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255077 |
|
|
Homo sapiens |
|
pmid |
sentence |
22493267 |
We show that BAALC overexpression occurs in the presence of the T allele of SNP rs62527607[GT], which creates a binding site for the activating RUNX1 transcription factor in the BAALC promoter region. The mechanism is demonstrated experimentally in vitro using luciferase reporter assays and electrophoretic mobility shift assay (EMSA) analysis. |
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