+ |
PSMF1 | down-regulates activity
binding
|
26S Proteasome |
0.506 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263341 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
23622245 |
We identify the ADP-ribosyltransferase tankyrase (TNKS) and the 19S assembly chaperones dp27 and dS5b as direct binding partners of the proteasome regulator PI31. TNKS-mediated ADP-ribosylation of PI31 drastically reduces its affinity for 20S proteasome alpha subunits to relieve 20S repression by PI31. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
TNKS2 | down-regulates quantity by destabilization
ADP-ribosylation
|
PSMF1 |
0.474 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263386 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
23622245 |
We identify the ADP-ribosyltransferase tankyrase (TNKS) and the 19S assembly chaperones dp27 and dS5b as direct binding partners of the proteasome regulator PI31. TNKS-mediated ADP-ribosylation of PI31 drastically reduces its affinity for 20S proteasome alpha subunits to relieve 20S repression by PI31. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
TNKS | down-regulates quantity by destabilization
ADP-ribosylation
|
PSMF1 |
0.479 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263387 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
23622245 |
We identify the ADP-ribosyltransferase tankyrase (TNKS) and the 19S assembly chaperones dp27 and dS5b as direct binding partners of the proteasome regulator PI31. TNKS-mediated ADP-ribosylation of PI31 drastically reduces its affinity for 20S proteasome alpha subunits to relieve 20S repression by PI31. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |