+ |
CNOT9 | form complex
binding
|
CCR4-NOT complex |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-268303 |
|
|
Homo sapiens |
|
pmid |
sentence |
19558367 |
In the present study, we examine the composition of the human Ccr4-Not complex in an in-depth proteomic approach using stable cell lines expressing tagged CNOT proteins. We find at least four different variants of the human complex, consisting of seven stable core proteins and mutually exclusive associated mRNA deadenylase subunits. Interestingly, human CNOT4 is in a separate approximately 200 kDa complex. Furthermore, analyses of associated proteins indicate involvement of Ccr4-Not complexes in splicing, transport and localization of RNA molecules. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CNOT9 | up-regulates activity
binding
|
GIGYF2 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260058 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
20878056 |
Through interaction analysis of RQCD1 with full-length or partial proteins of GIGYF1 and GIGYF2, segments corresponding to 620-665th and 667-712th amino acids were identified as potential interacting regions on GIGYF1 and GIGYF2, respectively, with RQCD1. we found that RQCD1 was required for enhancement of the interaction of Grb10 with GIGYF1 and GIGYF2 |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CNOT9 | up-regulates activity
binding
|
GIGYF1 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260059 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
20878056 |
Through interaction analysis of RQCD1 with full-length or partial proteins of GIGYF1 and GIGYF2, segments corresponding to 620-665th and 667-712th amino acids were identified as potential interacting regions on GIGYF1 and GIGYF2, respectively, with RQCD1. we found that RQCD1 was required for enhancement of the interaction of Grb10 with GIGYF1 and GIGYF2 |
|
Publications: |
1 |
Organism: |
Homo Sapiens |