Summary

Name PTPRU
Full Name Receptor-type tyrosine-protein phosphatase U
Synonyms R-PTP-U, EC 3.1.3.48, Pancreatic carcinoma phosphatase 2, PCP-2, Protein-tyrosine phosphatase J, PTP-J, hPTP-J, Protein-tyrosine phosphatase pi, PTP pi, Protein-tyrosine phosphatase receptor omicron, PTP-RO, Receptor-type protein-tyrosine phosphatase psi, R-PTP-psi | FMI, PCP2, PTPRO
Primary ID Q92729
Links - -
Type protein
Relations 1
Function Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis. {ECO:0000269|PubMed:10397721, ECO:0000269|PubMed:12501215, ECO:0000269|PubMed:16574648}.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png dephosphorylation CTNNB1 0.41
Publications: 1 Organism: Homo Sapiens