Summary

Name FRZB
Full Name Secreted frizzled-related protein 3
Synonyms sFRP-3, Frezzled, Fritz, Frizzled-related protein 1, FrzB-1 | FIZ, FRE, FRP, FRZB1, SFRP3
Primary ID Q92765
Links - -
Type protein
Relations 2
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png binding WNT8A 0.498
Publications: 1 Organism: Homo Sapiens
Tissue: Kidney
+ down-regulates img/direct_inhibition.png binding WNT1 0.534
Publications: 1 Organism: Homo Sapiens
Tissue: Kidney