| + |
PRKACB | up-regulates activity 
phosphorylation
|
GPKOW |
0.31 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266299 |
Ser27 |
SFGFTRTsARRRLAD |
|
|
| pmid |
sentence |
| 21880142 |
Using yeast two-hybrid screening with the PKA Cβ2 subunit as bait we identified GPKOW, also known as MOS2 homolog or T54 protein, as an interaction partner for Cβ2. PKA phosphorylates GPKOW at S27 and T316 in vitro. GPKOWs ability to bind RNA is sensitive to mutations of its PKA phosphorylation sites. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266311 |
Ser27 |
SFGFTRTsARRRLAD |
in vitro |
|
| pmid |
sentence |
| 21880142 |
Using yeast two-hybrid screening with the PKA Cβ2 subunit as bait we identified GPKOW, also known as MOS2 homolog or T54 protein, as an interaction partner for Cβ2. PKA phosphorylates GPKOW at S27 and T316 in vitro. GPKOWs ability to bind RNA is sensitive to mutations of its PKA phosphorylation sites. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266298 |
Thr316 |
GTASSRKtLWNQELY |
|
|
| pmid |
sentence |
| 21880142 |
Using yeast two-hybrid screening with the PKA Cβ2 subunit as bait we identified GPKOW, also known as MOS2 homolog or T54 protein, as an interaction partner for Cβ2.PKA phosphorylates GPKOW at S27 and T316 in vitro. GPKOWs ability to bind RNA is sensitive to mutations of its PKA phosphorylation sites. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266310 |
Thr316 |
GTASSRKtLWNQELY |
in vitro |
|
| pmid |
sentence |
| 21880142 |
Using yeast two-hybrid screening with the PKA Cβ2 subunit as bait we identified GPKOW, also known as MOS2 homolog or T54 protein, as an interaction partner for Cβ2.PKA phosphorylates GPKOW at S27 and T316 in vitro. GPKOWs ability to bind RNA is sensitive to mutations of its PKA phosphorylation sites. |
|
| Publications: |
4 |
Organism: |
, In Vitro |
| + |
PRKACA | up-regulates activity
phosphorylation
|
GPKOW |
0.31 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266309 |
Ser27 |
SFGFTRTsARRRLAD |
in vitro |
|
| pmid |
sentence |
| 21880142 |
PKA phosphorylates GPKOW at S27 and T316 in vitro. GPKOWs ability to bind RNA is sensitive to mutations of its PKA phosphorylation sites. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266308 |
Thr316 |
GTASSRKtLWNQELY |
in vitro |
|
| pmid |
sentence |
| 21880142 |
PKA phosphorylates GPKOW at S27 and T316 in vitro. GPKOWs ability to bind RNA is sensitive to mutations of its PKA phosphorylation sites. |
|
| Publications: |
2 |
Organism: |
In Vitro |
| + |
GPKOW | up-regulates quantity
binding
|
DHX16 |
0.843 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266312 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 25296192 |
In this report, we showed that GPKOW interacted directly with the DHX16/hPRP2 and with RNA. Immuno-depletion of GPKOW from HeLa nuclear extracts resulted in an inactive spliceosome that still bound DHX16. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266300 |
|
|
|
|
| pmid |
sentence |
| 25296192 |
In this report, we showed that GPKOW interacted directly with the DHX16/hPRP2 and with RNA. Immuno-depletion of GPKOW from HeLa nuclear extracts resulted in an inactive spliceosome that still bound DHX16. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens, |
3.0
GPKOW
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