+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
EFHC1 |
0.364 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266934 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
SPAG6 |
0.46 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266935 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
TUBA1A |
0.303 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266938 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
CETN2 |
0.36 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266930 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
TEKT2 |
0.331 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266937 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
Axonemal_Dynein |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266939 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
RFX3 | up-regulates activity
binding
|
FOXJ1 |
0.566 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266929 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
RFX3 acts as a transcriptional co-activator to FOXJ1 that enhances the expression of cilia-associated genes. FOXJ1 is an important regulator of cilia gene expression during ciliated cell differentiation, with RFX3 as a transcriptional co-activator to FOXJ1, helping to induce the expression of cilia genes in the process of ciliated cell differentiation of basal/progenitor cells. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
DNAI1 |
0.377 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266932 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
DNAH11 |
0.369 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266931 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
DNALI1 |
0.404 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266933 |
|
|
Homo sapiens |
|
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
TEKT1 |
0.373 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266936 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |