+ |
AURKA | up-regulates
phosphorylation
|
CETN2 |
0.495 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-174686 |
Ser170 |
LRIMKKTsLY |
Homo sapiens |
Breast Cancer Cell |
pmid |
sentence |
21731694 |
Our studies show that aurora a phosphorylates centrin at serine 170 in vitro and that the serine 170 phosphorylation affects the stability of centrin by regulating its interaction with apc/c. finally we demonstrated that phosphorylation of centrin serine 170 is an absolute requirement for aurora a-mediated centriole amplification. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
CETN2 |
0.36 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266930 |
|
|
Homo sapiens |
Basal Cell |
pmid |
sentence |
23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
PCM1 | up-regulates
relocalization
|
CETN2 |
0.511 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-94990 |
|
|
Homo sapiens |
|
pmid |
sentence |
12403812 |
Rna silencing of pcm-1 leads to reduced assembly of centrin, pericentrin, and ninein at the centrosome |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CCP110 | up-regulates activity
binding
|
CETN2 |
0.687 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265967 |
|
|
Homo sapiens |
|
pmid |
sentence |
16760425 |
We report that CP110 interacts with two different Ca2+-binding proteins, calmodulin (CaM) and centrin, in vivo. our data demonstrate a functional role for CaM binding to CP110 and suggest that CP110 cooperates with CaM and centrin to regulate progression through cytokinesis. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |