4.0
Summary
| Name |  UBE2E3View Modifications |
| Full Name | Ubiquitin-conjugating enzyme E2 E3 |
| Synonyms | E2 ubiquitin-conjugating enzyme E3, UbcH9, Ubiquitin carrier protein E3, Ubiquitin-conjugating enzyme E2-23 kDa, Ubiquitin-protein ligase E3 | UBCE4, UBCH9 |
| Primary ID | Q969T4 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | UBE2E3 | up-regulates quantity by stabilization 
sumoylation
|
NFKBIA | 0.345 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | hsa-miR-30a-3p | down-regulates quantity by destabilization 
post transcriptional regulation
|
UBE2E3 | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | hsa-mir-379-5p | down-regulates quantity by destabilization
post transcriptional regulation
|
UBE2E3 | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Ub:E1 (UBA1 substrate) | up-regulates activity
ubiquitination
|
UBE2E3 | 0.721 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Ub:E1 (UBA6 substrate) | up-regulates activity
ubiquitination
|
UBE2E3 | 0.611 |
| Publications: | 1 | Organism: | Homo Sapiens | |