+ |
UBE2E3 | up-regulates quantity by stabilization
sumoylation
|
NFKBIA |
0.353 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-270545 |
Lys21 |
EGPRDGLkKERLLDD |
Homo sapiens |
HEK-293 Cell, HeLa Cell |
pmid |
sentence |
10582246 |
In the presence of an E1 SUMO-1-activating enzyme, Ubch9 conjugated SUMO-1 to IkappaBalpha primarily on K21, which is also utilized for ubiquitin modification. Thus, SUMO-1-modified IkappaBalpha cannot be ubiquitinated and is resistant to proteasome-mediated degradation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
Ub:E1 (UBA1 substrate) | up-regulates activity
ubiquitination
|
UBE2E3 |
0.708 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-271330 |
|
|
Homo sapiens |
|
pmid |
sentence |
34199813 |
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
Ub:E1 (UBA6 substrate) | up-regulates activity
ubiquitination
|
UBE2E3 |
0.593 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-271364 |
|
|
Homo sapiens |
|
pmid |
sentence |
34199813 |
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t |
|
Publications: |
1 |
Organism: |
Homo Sapiens |