Relation Results

Name	RNF183
Full Name	E3 ubiquitin-protein ligase RNF183
Synonyms	RN183_HUMAN \|
Primary ID	Q96D59
Links	- -
Type	protein
Relations	3
Function	Acts as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (PubMed:29507230). Triggers apoptosis in response to prolonged ER stress by mediating the polyubiquitination and subsequent proteasomal degradation of BCL2L1 (PubMed:29507230). May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling (PubMed:26567849).