3.0
Summary
| Name |  LINGO1
|
| Full Name | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 |
| Synonyms | Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A | LERN1, LRRN6A |
| Primary ID | Q96FE5 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity). |
binding