4.0
Summary
| Name |  OTUD5View Modifications |
| Full Name | OTU domain-containing protein 5 |
| Synonyms | Deubiquitinating enzyme A, DUBA | |
| Primary ID | Q96G74 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro). |
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phosphorylation
deubiquitination